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Lees meer over de oorzaken van MS, symptomen, diagnose en mogelijke behandelingen.. You can then conserve your energy later when you feel. It is used off-label in MS to treat fatigue and sleepiness. 5,7–9 studies have suggested that high dosages of pemoline (75 mg/day) are needed to achieve any improvement in ms related fatigue, 7,10 but even with a high dosage the improvement was not …. Provigil was developed by Cephalon (now part of Teva Pharmaceuticals ) but is now available. Amongst them, the most commonly used is amantadine. Modafinil is a wakefulness-promoting agent approved to improve wakefulness in adults who experience excessive sleepiness due to obstructive sleep apnea or shift work sleep disorder. 4 out of 10 from a total of 58 ratings for the treatment of Fatigue. Filter by condition Modafinil rating summary 7. 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